Pierre Ronceray

Université Aix-Marseille, France

What can we learn from the stochastic trajectories of biological systems?

Abstract

Stochastic differential equations are often used to model the dynamics of living systems, from Brownian motion at the molecular scale to the dynamics of cells and animals. How does one learn such models from experimental data? This task faces multiple challenges, from information-theoretical limitations to practical considerations. I will present my recent and ongoing effort to develop new methods to reconstruct such stochastic dynamical models from experimental data, with a focus on robustness and data efficiency. This provides a generic means to quantify complex behavior and unfold the underlying mechanisms of an apparently erratic trajectory.

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